Homepage of Madalena Chaves


NEW ADDRESS:
I am now at the Institute for Systems Theory in Engineering, at the University of Stuttgart (since September 2005).
Check my new email and contacts here.

Thousand Island Lake, Ansel Adams Wilderness


This is the Thousand Island Lake, in the Ansel Adams Wilderness
, where I spent a week hiking (September 2003).

Sometime before that, in May 2003, I finished my PhD. in Mathematics, in the area of Control Theory. See links to some of my work below. And a list of recent presentations here.

Currently (until June 2005) I am a visiting scientist at sanofi-aventis, Bridgewater site (a French group, which is the world's third largest pharmaceutical company), and a visiting postdoc at the Dep. Mathematics, Rutgers University (contacts).





Publications and preprints:

M. Chaves, R. Albert and E.D. Sontag.
Methods of robustness analysis for Boolean models of gene control networks.
Submitted.

M. Chaves.
Input-to-state stability of rate-controlled biochemical networks.
SIAM J. Control and Optimization, in press.

M. Chaves, R. Albert and E.D. Sontag.
Robustness and fragility of Boolean models for genetic regulatory networks.
J. Theoretical Biology, 235(3)(2005), pp. 431-449.
(A version is available at http://arXiv.org/  as q-bio.MN/0501037.)

E.D. Sontag and M. Chaves.
Computation of amplification for systems arising from cellular signaling pathways.
Accepted for the 16th IFAC World Congress, Prague, Czech Republic, July 2005.

M. Chaves, E.D. Sontag and R.J. Dinerstein.
Gains and optimal design in signaling pathways.
Proc. Conf. Decision and Control (CDC'04), Paradise Island, The Bahamas, Dec. 2004.

M. Chaves, E.D. Sontag and R.J. Dinerstein.
Optimal length and signal amplification in weakly activated signal transduction cascades.
J. Physical Chemistry B 108(2004), pp. 15311-15320.
(A previous version is available at http://arXiv.org/  as math.OC/0311357.)

M. Chaves, E.D. Sontag and R.J. Dinerstein.
Steady-states of receptor--ligand dynamics: a theoretical framework.
J. Theoretical Biology 227(2004), pp. 413-428.

M. Chaves.
Observer design for a class of nonlinear systems, with applications to biochemical networks.
PhD. thesis, Rutgers University, NJ, May 2003.

S. Glavaski, M. Chaves, R. Day, P. Nag, A. Wiliams and  W. Zhang.
Vehicle networks: achieving regular formation.
Proc. American Control Conf. (ACC'03), Denver, Colorado, June 2003.

M. Chaves.
A parameter-robust observer as an application of ISS techniques.
Proc. Int. Symp. Mathematical Theory of Networks and Systems
(MTNS'02), South Bend, Indiana, Aug. 2002.

M. Chaves and E.D. Sontag.
State-estimators for chemical reaction networks of Feinberg-Horn-Jackson zero deficiency type.
European J. Control 8(2002), pp. 343-359.

M. Chaves and E.D. Sontag.
Observers for chemical reaction networks.
Proc. European Control Conf. (ECC'01), Porto, Portugal, Sep. 2001.

M. Chaves and E.D. Sontag.
An alternative observer for zero deficiency chemical networks.
Proc. IFAC Nonlinear Control Systems Symp. (NOLCOS'01),
St. Petersburg, Russia, July 2001.

F. Albertini and M. Chaves.
Stabilizability of continuous time systems with saturation nonlinearities.
Report of a Summer research project  at Rutgers University, 1998/99.



Recent Meetings and Presentations:

"Zero-deficiency chemical networks and the analysis of receptor/ligand interactions" .
Invited colloquium at the Dep. Mathematics, George Washington University, Washington DC (Apr. 2005).

"System gain and optimal length for signal transduction cascades".
Invited presentation at the Northeast Nonlinear and Hybrid Control Workshop , Rensselaer Polytechnic Institute, Troy, NY (Apr. 2005) .

"Some theoretical aspects of cell signaling: receptor-ligand interactions and signal amplification cascades".
Invited seminar at the Hamilton Institute , Maynooth, Ireland (Feb. 2005).

"Gains and optimal design in signaling pathways".
Presentation at the Conference on Decision and Control (CDC'04), Paradise Island, The Bahamas (Dec. 2004).

"Modeling calcium signaling and its connection to receptor-ligand interactions".
Invited seminar at the Systems Biology Group, Institut Pasteur, Paris, France (Sep. 2004).

"Some theoretical aspects of cell signaling: receptor-ligand interactions and signal amplification cascades".
Invited seminar at the Institut fur Systemtheorie Technischer Prozesse, Universitat Stuttgart, Germany (Aug. 2004).

"A model of receptor-ligand interactions, and cell signaling".
Invited presentation at the workshop: Dynamics, control and computation in biochemical networks. Banff International Research Station, Canada (Aug. 2004).

"Un mod\`ele pour les interactions r\'ecepteur-ligand".
Presentation at the Forum des Jeunes Math\'ematiciennes: Math\'ematiques, Informatique et Sciences du Vivant. Institut Henri Poincar\'e, Paris, France (Jan. 2004).

"A parameter-robust observer as an application of ISS techniques".
Presentation at the Symposium on Mathematical Theory of Networks and Systems (MTNS'02), South Bend, Indiana (Aug. 2002).

"Observers for chemical reaction networks".
Presentation at the European Control Conf. (ECC'01), Porto, Portugal (Sep. 2001).

"An alternative observer for zero deficiency chemical networks".
Presentation at the IFAC Nonlinear Control Systems Symposium (NOLCOS'01), St. Petersburg, Russia (July 2001).



madalena.jpg

Contacts

 
1. sanofi-aventis,
Building JR1 - 0360,
1041 Route 202-206 North,
Bridgewater, NJ 08807
Tel: 908-231-2157




2. Dep. Mathematics,  Rutgers University,
Hill Center, Busch Campus,
110 Frelinghuysen Rd., Piscataway, NJ 08854
Tel: 732-445-7925
E-mail: madalena -at- math.rutgers.edu

Last updated: 5/2005