Seminars & Colloquia Calendar

Download as iCal file

Mathematical Physics Seminar

Phase separation in biological cells

Ned Wingreen - Princeton University

Location:  Zoom
Date & time: Wednesday, 09 March 2022 at 10:45AM - 11:45PM

Abstract: An emerging mechanism for intracellular organization is biomolecular phase separation into condensates of proteins and nucleic acids. However, the physical processes that govern the distribution of condensate sizes remain unclear. We utilize a combination of experimental synthetic and native condensates and simulations to probe the underlying coarsening mechanisms determining condensate size. Distributions range from exponential to power-law, reflecting the relative rates of nucleation and coalescence kinetics. We succinctly account for these differences by indentifying a “rich get richer” effect, whose extent may play a general role in the determination of condensate size distributions.

Special Note to All Travelers

Directions: map and driving directions. If you need information on public transportation, you may want to check the New Jersey Transit page.

Unfortunately, cancellations do occur from time to time. Feel free to call our department: 848-445-6969 before embarking on your journey. Thank you.