Seminars & Colloquia Calendar

Download as iCal file

Mathematical Physics Seminar

The predictive power of theoretical biology

Jean-Pierre Eckmann - University of Geneva

Location:  Zoom
Date & time: Wednesday, 23 March 2022 at 10:45AM - 11:45AM

Abstract: I will argue, supported by an experiment, that theoretical biology moves (very slowly) in a direction where predictions (as in theoretical physics) become possible.
Starting from insights for a simple mechanical-genetic model of protein and the interpration of its spectral properties, one can formulate some predictions on the presence or absence of an effect when the protein is mutated. The results suggest that only mutations at specific positions in the gene sequence have a critical effect on the function.
These predictions have then been checked in a delicate experiment with actual mutations in the protein Guanylate kinase. A clear signal confirms the theoretical prediction. 

Some of the people involved in this work are  Tsvi Tlusty, Marta Siek, Jacques Rougemont, Elisha Moses, Eyal Weinreb, Albert Libchaber, Stan Leibler

Special Note to All Travelers

Directions: map and driving directions. If you need information on public transportation, you may want to check the New Jersey Transit page.

Unfortunately, cancellations do occur from time to time. Feel free to call our department: 848-445-6969 before embarking on your journey. Thank you.