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Mathematical Physics Seminar

Uri Alon - Aging has nearly universal quantitative patterns

Location:  zoom
Date & time: Wednesday, 10 January 2024 at 10:45AM - 11:45AM

Uri Alon – Weizmann Institute of Science

Wednesday, January 10th, 10:45AM EST (Zoom meeting starts at 10:30 EDT) 

Aging has nearly universal quantitative patterns


We explain them using a stochastic ode for damage production and removal, deduced from experiments on damage dynamics in mice and in individual bacteria, the latter done by us. This simple model explains a wide range of phenomena in human aging and age related diseases. The talk will assume no knowledge in biology.


Yang, Y., Karin, O., Mayo, A. et al. Damage dynamics and the role of chance in the timing of E. coli cell death. Nat Commun 14, 2209 (2023).

Compression of sickspan by interventions that steepen the survival curve
Yifan Yang, Avi Mayo, Tomer Levy, Dan Jarosz, Uri Alon
bioRxiv 2023.10.04.560871; doi:

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