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UID:e2e1676c5e677b0c29d2b2531975c8ee
CATEGORIES:Mathematical Physics Seminar
CREATED:20220607T103850
SUMMARY:Flows and instabilities in cellular biomechanics
LOCATION:Zoom
DESCRIPTION:Flows in the fluidic interior of living cells can serve function, and by th
 eir structure shed light on how forces are exerted within the cell. Some of
  these flows can arise through novel collective instabilities of the cytosk
 eleton, the set of polymers, cross-linkers, and molecular motors that under
 lie much of the mechanics within and between cells. I'll discuss experiment
 s, mathematical modeling and analysis, and simulations of two such cases. O
 ne is understanding the emergence of \n cell-spanning vortical flows in dev
 eloping egg cells and driven by cargo-bearing molecular motors, while the o
 ther arises from studying the nature of force transduction in the dynamics 
 of microtubule arrays inside of synthetic cells. Both show the importance o
 f polymer density in determining dynamics and time-scales, and have require
 d the development of new coarse-grained models and simulation methods.\n
X-ALT-DESC;FMTTYPE=text/html:<p style="text-align: center;">Flows in the fluidic interior of living cell
 s can serve function, and by their structure shed light on how forces are e
 xerted within the cell. Some of these flows can arise through novel collect
 ive instabilities of the cytoskeleton, the set of polymers, cross-linkers, 
 and molecular motors that underlie much of the mechanics within and between
  cells. I'll discuss experiments, mathematical modeling and analysis, and s
 imulations of two such cases. One is understanding the emergence of <br /> 
 cell-spanning vortical flows in developing egg cells and driven by cargo-be
 aring molecular motors, while the other arises from studying the nature of 
 force transduction in the dynamics of microtubule arrays inside of syntheti
 c cells. Both show the importance of polymer density in determining dynamic
 s and time-scales, and have required the development of new coarse-grained 
 models and simulation methods.</p>
CONTACT:Michael J. Shelley - NYU
DTSTAMP:20260828T041413
DTSTART;TZID=America/New_York:20220615T104500
DTEND;TZID=America/New_York:20220615T114500
SEQUENCE:0
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