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Krawtchouk polynomials constitute a family of orthogonal polynomials with applications in probability theory. In 2012, Iliev gave a Lie-theoretic interpretation of the multivariate Krawtchouk polynomials using certain representations of the Lie algebra sl_n. In this talk, we will present a superization of this interpretation, introduce super Krawtchouk polynomials with anticommuting variables, and explore their connection with zonal spherical functions on oriented Grassmannians. This is a joint work in progress with Plamen Iliev.